Damsel: analysis and visualisation of DamID sequencing in R

CG Page; A Londsdale; KA Mitchell; J Schröder; KF Harvey; A Oshlack

Journal article

Damsel: analysis and visualisation of DamID sequencing in R

CG Page, A Londsdale, KA Mitchell, J Schröder, KF Harvey, A Oshlack

Bioinformatics | OXFORD UNIV PRESS | Published : 2024

DOI: 10.1093/bioinformatics/btae695

Open access

Abstract

DamID sequencing is a technique to map the genome-wide interaction of a protein with DNA. Damsel is the first Bioconductor package to provide an end to end analysis for DamID sequencing data within R. Damsel performs quantification and testing of significant binding sites along with exploratory and visual analysis. Damsel produces results consistent with previous analysis approaches.

University of Melbourne Researchers

Katrina Mitchell Author

Jan Schroeder Author

Kieran Harvey Author

Alicia Oshlack Author

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Grants

Awarded by National Health and Medical Research Council

Funding Acknowledgements

This work was supported by an Investigator grant [APP1196256 to A.O.] from the National Health and Medical Research Council of Australia. This work was supported by an Investigator grant [APP1194467 to K.F.H.] from the National Health and Medical Research Council of Australia.